Isolation rearing impairs novel object recognition and attentional set shifting performance in female rats
نویسندگان
چکیده
منابع مشابه
Experimental sleep fragmentation impairs attentional set-shifting in rats.
STUDY OBJECTIVE To evaluate the effect of experimental sleep fragmentation (sleep interruption; SI) on complex learning in an intradimensional-extradimensional (ID/ED) set-shifting task in rats. DESIGN A sleep fragmentation paradigm of intermittent forced locomotion was validated in adult rats by examining electrographic effects. Discrimination task performances were assessed in rats followin...
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Adolescent rats show immaturities in executive function and are less able than adult rats to learn reinforcement reversals and shift attentional set. These two forms of executive function rely on the functional integrity of the orbitofrontal and prelimbic cortices respectively. Drugs used to treat attention deficit disorder, such as atomoxetine, that increase cortical catecholamine levels impro...
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Ischemic stroke causes the depletion of energy and induces excitotoxicity and neuroinflammation in the brain that results from thrombotic blockage. Cerebral ischemia leads to many types of memory loss, including impairment of working, spatial and object recognition memoreis. Curcumin shows strong anti-oxidoinflammatory activities but it terapathics limited by its low solubility in water and cor...
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Introduction: Mood disorders such as anxiety and depression are common following menopause and andropause. The lack of sex steroid hormones is suggested as the primary cause of these disturbances. The level of luteinizing hormone (LH) would also rise 3-4 times than normal in these people. The potential effects of LH on mood and cognitive symptoms following menopause and andropause are not clear...
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ژورنال
عنوان ژورنال: Journal of Psychopharmacology
سال: 2008
ISSN: 0269-8811,1461-7285
DOI: 10.1177/0269881108093842